Skin aging and Skin rejuvenation: science, prevention and recovery

The skin is our largest organ – a barrier against the outside world, but also a mirror of our internal health and biological age. Skin aging is more than an aesthetic phenomenon: it is an expression of deeper biological processes influenced by gene expression, inflammation, oxidative stress, nutrient deficiencies, hormonal changes and environmental factors.

Intrinsic and Extrinsic Skin Aging

Skin aging has two main pathways:

– Intrinsic: genetically determined, biological aging, driven by telomere shortening, epigenetic changes, reduced cell renewal and collagen synthesis.
– Extrinsic: driven by external factors such as UV radiation, air pollution, smoking, nutritional deficiencies and chronic stress. These accelerate inflammation and glycation processes in the skin.

Epigenetic Regulation of Skin Aging

The expression of genes that regulate collagen, elastin and antioxidants can decrease due to epigenetic aging. However, this gene regulation is reversible – a key principle within epigenetic medicine. Through targeted interventions, we can positively modulate gene expression, reduce oxidative damage and promote skin regeneration.

Orthomolecular and Nutritional Interventions.

At the Linus Pauling Prevention Center, we approach skin aging from an integrative, cell biological perspective. Key focuses include:

– Antioxidants (such as vitamins C, E, glutathione, astaxanthin): protection against oxidative damage and stimulation of collagen synthesis.
– Omega-3 fatty acids: attenuation of low-grade inflammation.
– Coenzyme Q10 and NAD⁺-precursors: support mitochondrial energy production in skin cells.
– Polyphenols and phytonutrients: activation of protective gene pathways (such as Nrf2).
– Zinc, selenium and silicon: crucial for skin repair, keratin formation and enzyme activity.

Skin Diagnostics: Objective Analysis

A proper approach starts with a correct assessment of the skin condition. In the  Beauty expert Gent, part of the Linus Pauling Prevention Center, we perform an objective skin diagnosis via skin camera technology. With this, we map skin texture, hydration, pore structure, pigmentation, elasticity and signs of oxidative damage in detail. This analysis is the starting point for a personalized treatment plan.

Local Skin Treatment: Micro-Needling and Mesoboost

For external skin rejuvenation, you will be guided by Marina Dasdamirova, who specializes in dermacosmetic treatments. In her practice within the LPPC, she focuses on:

Micro-needling :

a controlled stimulation of the skin with fine needles, activating the natural production of collagen and elastin. This improves skin texture, reduces wrinkles and evens out the complexion.

These local treatments are closely coordinated with the internal approach to skin rejuvenation, creating a synergistic effect between cell biological optimization and superficial skin improvement.

Tandem Faché - Dasdamirova: Beautiful on the outside and healthy on the inside

Skin rejuvenation is not a matter of superficial correction, but of a comprehensive approach. Within the Linus Pauling Prevention Center, we unite medical depth and aesthetic expertise in one integrated course. The tandem Faché – Dasdamirova combines:

– medical epigenetics and orthomolecular medicine
– scientific skin diagnostics
– targeted, skin-friendly treatment techniques

Beautiful on the outside and healthy on the inside is not a slogan, but our philosophy.