Microbiome analysis at the Linus Pauling Prevention Center
From gut flora to systemic health: the microbiome as a clinical key
The human gut microbiome – or more precisely, the intestinal microbiome – has become one of the most researched regulators of health and disease in recent years. Not as hype, but as a complex, dynamic and clinically relevant ecosystem that acts on immunity, metabolic balance, hormonal regulation, neuroinflammation and epigenetic modulation.
At the Linus Pauling Prevention Center, we consider the microbiome not as a trendy tool, but as a biological mirror of lifestyle, environment, nutrition and systemic health. For us, therefore, the analysis of the microbiome is not an end in itself, but a possible supporting link within a deep preventive and personalized pathway.
When and why microbiome analysis?
We do not prescribe microbiome testing by default for every patient. Only in clear clinical indications, or when the context calls for it, we recommend the use of this diagnostic. Some indications:
– Chronic inflammatory complaints (such as PDS, chronic constipation, bloated abdomen, unexplained fatigue)
– Metabolic disorders (such as insulin resistance, fatty liver, weight fluctuations)
– Immune dysfunction (frequent infections, low-grade inflammation, autoimmunity)
– Neuropsychological symptoms (brain fog, mood disorders, sleep disturbances)
– Aftercare after antibiotic or chemotherapy
– For structural lifestyle reprogramming (supported by nutrition and supplementation advice)
What exactly are we analyzing?
Depending on the indication, we refer for a standardized and scientifically validated microbiome examination, performed in an accredited laboratory. This may include the following parameters:
– Diversity and stability of the intestinal flora.
– Dominant bacterial groups (such as Firmicutes/Bacteroidetes ratio)
– Mucus-producing and butyrate-forming strains (e.g. Akkermansia, Faecalibacterium)
– Pathogenic or inflammatory overgrowth
– Digestive residues and fatty acid profile
– Zonulin levels or markers of intestinal permeability
– SCFA (short-chain fatty acids) profile.
Interpretation in context: no one-size-fits-all
A microbiome analysis has value only when it is interpreted medically and individually. Within the Linus Pauling Prevention Center, we link the results to:
– Lifestyle, dietary habits, stress profile
– Clinical complaints and history
– Inflammatory and metabolic biomarkers
– Genetic or epigenetic predisposition
– Medication and antibiotic use
– Dietary intolerances or gut-related syndromes
The analysis does not serve a commercial supplement sale, but a guided medical counseling process with emphasis on nutrition, lifestyle, targeted supplementation and restoration of barrier functions.
Relevance within the LPPC
At the LPPC, epigenetic clocks and telomere measurements are integrated into the preventive consultation model, with a focus on:
– Early detection of accelerated biological aging
– Monitoring interventions: lifestyle changes, nutritional interventions, bioactive substances (bioceuticals), stress management
– Personalized advice based on measurable parameters
– Motivational communication: patients gain insight into their internal aging process and are encouraged to actively adjust it
An ethically based use of advanced diagnostics
The Linus Pauling Prevention Center does not conduct laboratory testing itself, nor are we associated with commercial labs or supplement suppliers. Our role is that of medical supervisor and director: we select reliable analyses, help patients choose based on added scientific value, and provide interpretation and follow-up within a clinical ethical framework.
The microbiome is not a fashion, but a medically relevant ecosystem
We believe that the gut is not only “our second brain,” but an epigenetic control organ with impact on the whole person. Microbiome analysis is not a panacea, but a powerful tool within a new medicine that starts from recovery, personalization and prevention.